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ey0016.11-11 | Brown Adipose Tissue: The Story Goes On | ESPEYB16

11.11. Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues

A Raajendiran , G Ooi , J Bayliss , PE O'Brien , RB Schittenhelm , AK Clark , RA Taylor , MS Rodeheffer , PR Burton , MJ Watt

To read the full abstract: Cell Rep 2019; 27(5): 152840These authors used FACS cell sorting, gene expression profiling, and metabolic and proteomic analyses to identify three distinct adipocyte progenitor cell (APCs) subtypes that reside in human white adipose tissues. Although they retain comparable differentiation capacity, they have different molecular profiles and give rise to ...

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ey0016.12-14 | Lipid Metabolism | ESPEYB16

12.14. An integrative systems genetic analysis of mammalian lipid metabolism

BL Parker , AC Calkin , MM Seldin , MF Keating , EJ Tarling , P Yang , SC Moody , Y Liu , EJ Zerenturk , EJ Needham , ML Miller , BL Clifford , P Morand , MJ Watt , RCR Meex , KY Peng , R Lee , K Jayawardana , C Pan , NA Mellett , JM Weir , R Lazarus , AJ Lusis , PJ Meikle , DE James , TQ de Aguiar Vallim , BG Drew

Nature 2019;567:187193.URL https://doi.org/10.1038/s41586-019-0984-ySummary: Novel diagnostic and prognostic biomarkers in the blood that can predict early fatty liver disease were identified, using a proteomic and lipidomic-wide systems genetic approach in 107 genetically distinct mouse strains. In addition, the novel lipid-regulatory protein, PSMD9, was identified as...

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ESPE Yearbook of Paediatric Endocrinology

11.11. Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues

12.14. An integrative systems genetic analysis of mammalian lipid metabolism

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